ANTICOAGULANT THERAPY IN “ACUTE PROGRESSIVE” GLOMERULONEPHRITIS

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'Pulse' methylprednisolone and cyclophosphamide therapy in idiopathic rapidly progressive glomerulonephritis.

The clinical report of a 31-year-old man who developed acute renal failure due to idiopathic rapidly progressive glomerulonephritis is presented. Intravenous pulse methylprednisolone therapy in combination with cyclophosphamide resulted in marked improvement in renal function. The literature dealing with pulse therapy is reviewed.

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Rapidly Progressive Glomerulonephritis are a group of renal diseases which are still posing serious threat to human health and survival. They are all characterised by acute and rapid deterioration of renal function. Renal biopsy reveals extracapillary glomerulonephritis, most frequently circumferential and diffuse, and immunofluorescence findings continue to represent the most important clue to...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1974

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197404000-00696